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International Journal of Toxicology
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Vaginal and Rectal Administration

Carol S. Auletta

Pharmaco LSR, Inc., East Millstone, New Jersey, U.S.A.

Vaginal and rectal routes of administration of test substances are not often used in animal testing procedures. However, these routes are almost obligatory when therapeutic agents intended for vaginal or rectal use in humans have to be evaluated for safety in animals. Applicable study designs and experiences with these routes are described in this report.

Key Words: Vaginal administration • Rectal administration • Mucous membrane toxicity

International Journal of Toxicology, Vol. 13, No. 1, 48-63 (1994)
DOI: 10.3109/10915819409140655
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