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Scrutinizing Three Trichloroethylene Carcinogenicity Classifications in the European Union—Implications for the Risk Assessment Process

Philosophy Unit, Royal Institute of Technology, Stockholm, Sweden; and Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden

In this paper, carcinogenicity classifications of the chlorinated solvent trichloroethylene (TCE) made by the European Union Commission Expert Groups in 1976, 1988, and 2001 are scrutinized and alternative classifications are proposed. It is argued that the TCE database at these three points in time could have been interpreted to fulfill the criteria for stricter classifications than those actually made. Implications of this for the classification process are discussed.

Key Words: Carcinogenicity • Classification Criteria • Downstream Regulations • Precautionary Principle • Regulatory Toxicology • Risk Management

International Journal of Toxicology, Vol. 21, No. 6, 441-450 (2002)
DOI: 10.1080/10915810290169864


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