| Sign In to gain access to subscriptions and/or personal tools. |
The Case against Universal Varicella VaccinationMedical Veritas International Inc., Pearblossom, California, USA Correspondence: Address correspondence to Gary S. Goldman, PhD, Medical Veritas International Inc., P.O. Box 847, Pearblossom, CA 93553, USA. E-mail:pearblossominc{at}aol.com In 1995, the United States became the first country to implement a Universal Varicella Vaccination Program. Several questions remain: Is the varicella (chickenpox) vaccine needed? Is it cost effective as a routine immunization for all susceptible children? Or is it more beneficial for the disease to remain endemic so that adults may receive periodic exogenous exposures (boosts) that help suppress the reactivation of herpes zoster (shingles). In addition, as vaccination coverage becomes widespread, does loss of immunologic boosting cause a decline in vaccine efficacy and result in a reduced period of immunity? Scientific literature regarding safety of the varicella vaccine and its associated cost-benefit analysis have often reported optimistic evaluations based on ideal assumptions. Deleterious outcomes and their associated costs must be included when making a circumspect assessment of the Universal Varicella Vaccination Program.
Key Words: Herpes Zoster • Universal Varicella Vaccination Program • Varicella Immunization • Varicella Vaccine Adverse Reactions • Varicella Vaccine Efficacy
International Journal of Toxicology, Vol. 25, No. 5,
313-317 (2006) |
||||
 |
|
|
 |
|
Sign In to gain access to subscriptions and/or personal tools.
