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International Journal of Toxicology
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Article

Evaluation of Mercury Contamination in Smilax myosotiflora Herbal Preparations

Hooi-Hoon Ang
Kheng-Leng Lee

School of Pharmaceutical Sciences, Universiti Sains Malaysia, Minden, Penang, Malaysia

Correspondence: Address correspondence to Associate Professor Dr. Hooi-Hoon Ang, School of Pharmaceutical Sciences, Universiti Sains Malaysia. Minden, 11800, Penang, Malaysia. E-mail:hhang{at}usm.my

The DCA (Drug Control Authority) of Malaysia implemented phase 3 registration of traditional medicines in January 1992 with special emphasis on the quality, efficacy, and safety of all dosage forms of these medicines. For this reason, a total of 100 herbal products containing Smilax myosotiflora were purchased in the Malaysian market and analyzed for mercury content, as mercury is a recognized reproductive toxicant. The products were analyzed using cold vapor atomic absorption spectrophotometry. It was found that 89% of the above products do not exceed 0.5 ppm of mercury. Heavy metal poisoning such as mercury has been associated with traditional medicines. Therefore, it is important that doctors and health care practitioners are aware of these risks and finding ways to minimize them, including questions pertaining to the use of these remedies during the routine taking of a patient’s history.

Key Words: Atomic Absorption Spectrophototneter • Drug Control Authority Malaysia • Mercury • Quality Requirement for Traditional Medicines • Smilax myosotiflora

International Journal of Toxicology, Vol. 26, No. 5, 433-439 (2007)
DOI: 10.1080/10915810701583036
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