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International Journal of Toxicology
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5 Addendum to the Final Report on the Safety Assessment of 2-Bromo-2-Nitropropane-1,3-Diol

A literature review of test data that have become available since the 1979 toxicological safety report on 2-Bromo-2-Nitropropane-1,3-Diol (BNPD) is presented and discussed. The earlier conclusion that BNPD is safe as a cosmetic ingredient at concentrations up to 0.1% except under circumstances where its action with amines or amides can result in the formation of nitrosamines or nitrosamides is reaffirmed. The new data suggest the possibility that when it is absorbed, this ingredient may contribute to endogenous formation of nitrosamines in humans.

International Journal of Toxicology, Vol. 3, No. 3, 139-155 (1984)
DOI: 10.3109/10915818409010519
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