This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Add to Saved Citations Download to citation manager Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Ganther, H.E. Search for Related Content PubMed Articles by Ganther, H.E. Social Bookmarking                         What's this?

Pathways of Selenium Metabolism Including Respiratory Excretory Products

Department of Nutritional Sciences 1415 Linden Drive Madison, WI 53706

Selenium occurs in a variety of different chemical forms in plants and animals. Plants take up inorganic forms of selenium and make numerous selenium analogs of sulfur compounds. Exclusion of selenium from proteins is characteristic of plant species able to tolerate high concentrations of selenium. Animals metabolize both inorganic and organic forms of selenium into biologically active compounds, including selenocysteine in glutathione peroxidase. Intermediary metabolism of selenium in animals characteristically involves reduction and methylation, resulting in the excretion of urinary or respiratory metabolites that include the trimethylselenonium ion and dimethylselenide. Some mechanisms for reduction and methylation of selenium in animals are discussed, as well as the effects of methylation on toxicity.

International Journal of Toxicology, Vol. 5, No. 1, 1-5 (1986)
DOI: 10.3109/10915818609140731


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?