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International Journal of Toxicology
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Psychotic Reactions Following the Naive Ingestion of an Anorectic, Phenylpropanolamine, in Psychiatric Patients

B. C. Scavullo

Clinical Instructor in Psychiatry, Department of Psychiatry, Medical College of Virginia, Richmond, VA.

B. Dementi

7605 Forest Ave., Suite 414 Richmond, VA 23229

Two clinical case histories are presented that indicate that naive ingestion of the anorectic, phenylpropanolamine, may induce psychotic reactions in patients with preexisting diagnosed psychiatric disturbance. These clinical observations and concerns are buttressed by a review of the scientific literature relevant to the psychotic inducing effects of phenylpropanolamine and structurally similar sympathomimetic derivatives of β-phenylethylamine, such as amphetamine and ephedrine.

International Journal of Toxicology, Vol. 5, No. 6, 577-581 (1986)
DOI: 10.3109/10915818609141026
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