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International Journal of Toxicology
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The Rat Adrenal Medulla. I. The Normal Adrenal

A. S. Tischler, M.D.

Department of Pathology Tufts University School of Medicine 136 Harrison Avenue Boston, MA 02111

R. A. Delellis

Department of Pathology Tufts University School of Medicine 136 Harrison Avenue Boston, MA 02111

The morphology and physiology of the adrenal medulla are described, emphasizing the rat medulla as an experimental model. Current concepts are reviewed relating to the development of medullary cell lineages and to factors that affect synthesis, storage, and secretion of hormones in the adrenal medulla. The pathophysiological implications of adrenal medullary cells as a multimessenger system are discussed.

International Journal of Toxicology, Vol. 7, No. 1, 1-21 (1988)
DOI: 10.3109/10915818809078700


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