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International Journal of Toxicology
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Mechanisms of Asbestos Carcinogenicity

Peter Voytek

Clement Associates 9300 Lee Highway Fairfax, Virginia 22031-1207

Miriam Anver

Clement Associates 9300 Lee Highway Fairfax, Virginia 22031-1207

Todd Thorslund

Clement Associates 9300 Lee Highway Fairfax, Virginia 22031-1207

Jill Conley

Clement Associates 9300 Lee Highway Fairfax, Virginia 22031-1207

Elizabeth Anderson

Clement Associates 9300 Lee Highway Fairfax, Virginia 22031-1207

We present a brief review of different potential mechanisms at the molecular and cellular levels that may be involved in asbestos-induced carcinogenicity. The usefulness of considering such mechanisms in developing appropriate biologically based models to estimate carcinogenic risk at environmental levels of asbestos fibers is discussed.

International Journal of Toxicology, Vol. 9, No. 5, 541-550 (1990)
DOI: 10.3109/10915819009078762
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